SEVERE FORM OF CROHN’S DISEASE IN COMBINATION WITH AUTOIMMUNE LIVER DISEASE
نویسندگان
چکیده
منابع مشابه
Antibodies to conformational epitopes of soluble liver antigen define a severe form of autoimmune liver disease.
Prevalence and clinical relevance of antibodies to soluble liver antigen (tRNP((Ser)Sec)/SLA) in autoimmune hepatitis (AIH) have been investigated using partially purified or prokaryotically expressed antigen. The aim of this study was to improve the detection of anti-tRNP((Ser)Sec)/SLA by establishing an immunoassay that was able to identify antibodies directed to conformational epitopes and t...
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Autoimmune liver disorders are characterised by an inflammatory liver histology, circulating non-organ specific autoantibodies and increased levels of immunoglobulin G (IgG) in the absence of a known aetiology. They respond to immunosuppressive treatment, which should be instituted as soon as diagnosis is made. Liver disorders with a likely autoimmune pathogenesis include autoimmune hepatitis (...
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ژورنال
عنوان ژورنال: VESTNIK KHIRURGII IMENI I.I.GREKOVA
سال: 2018
ISSN: 0042-4625
DOI: 10.24884/0042-4625-2018-177-3-54-56